DIPHARMA is the study of how genetic factors influence the way a person responds to medications. PGx combines the study of pharmacology (study of how drugs work in the body) and genomics (study of genes and their functions). PGx is now being used to help physicians select safe and effective medications for their patients based on their unique genetic makeup.
There are certain genes that contain instructions to build proteins called enzymes. These enzymes are involved in the breakdown of many drugs in the body, mainly in the liver. People have different versions of these genes that produce enzymes with different levels of activity (for example, slow, normal or fast). As a result, people may vary in the speed or speed with which they break down and eliminate drugs from their bodies, and this may influence the proper functioning of a medication or the risk of side effects for that person.
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